Which of the following actions will NOT cause an article to be misbranded?

The correct answer reflects the understanding that not all actions considered problematic under pharmaceutical regulations categorize a product as misbranded. In this case, advertising an article in a false or misleading manner does indeed constitute a violation of the law, particularly related to misbranding, but it does not alter the characteristics of the product itself. Misbranding involves specific labeling issues and can include factors such as inadequate information provided to patients or consumers, misleading branding, or omissions of critical information.

In contrast, the other actions clearly define misbranding based on their impact on the product’s labeling and the information provided. For example, discarding a package insert removes crucial information a patient or healthcare provider needs, which directly violates labeling requirements. Similarly, failing to include the established name on the packaging can confuse consumers and health care providers, impacting the safe use of the medication. Lastly, including a coloring agent that is not listed in the ingredients poses safety concerns, as it can mislead consumers regarding the composition and safety of the drug.

Therefore, while misleading advertising is indeed illegal and detrimental to public safety, it is an external factor that does not change the product's inherent characteristics or labeling requirements, distinguishing it from the definitive actions that lead to misbranding as outlined by pharmacological regulations.